Anti-aging research

XPRIZE Healthspan is a $111M prize competition aiming to incentivize the development of therapeutics that significantly extend healthspan.

Metformin is used for type 2 diabetes treatment, however, it has recently gained significant attention in the field of anti-aging.

This summary highlights what we currently know of telomeres and the telomerase enzyme as potential anti-aging targets.

Rapamycin is used as an immunosuppressant, however, it has recently gained significant attention in the anti-aging research communities.

A recent study explores the potential of reversing age-related biological changes by targeting the insulin/IGF-1 signaling pathway

A recently published research review explores ferroptosis and its significant implications for aging and age-related diseases.

Research suggests that an Astragalus-based supplement may help lengthen telomeres, and thereby reduce cellular age-related decline.

Recent research has identified HAPLN1 (hyaluronan and proteoglycan link protein 1) as a promising factor for rejuvenating aged skin.

Research shows that cellular senescence can play a positive role in tissue repair, particularly in the meniscus of the knee.

A research review suggests that combining mTOR inhibitors and SGLT-2 inhibitors could provide benefits in slowing down the aging process.

Research suggests that targeting multiple aspects of aging through combination therapies could be more effective than single interventions.

Research shows how Amyloid Beta (Aβ) may accelerate aging via protein insolubility, and identifies Urolithin A as a potential solution.

A recent study using CRISPR-Cas9 gene-editing technology reveals Slc2a4 as key regulator of brain health and aging in neural stem...

Recent research found that CD133+ stem cells restores the function of blood vessels and extends lifespan in aging mice.

A combination of the three known drugs rapamycin, acarbose, and phenylbutyrate was shown to prevent age-related cognitive decline in mice.

Recent research explores how aging alters the behavior of neural stem cells and investigates potential methods to restore their function.

Researchers have discovered that the gene OSER1 plays a key role in managing oxidative stress and extending lifespan in multiple...

Recent research has identified a small molecule named miR-29 as a significant regulator of aging and potential anti-aging target.

Research suggests SGLT2 inhibitors may remove harmful senescent cells, which accumulate as we age and contribute to age-related diseases.

Research has discovered that moderate cold temperature extends longevity and reduce the risk of age-related diseases in human cells.

A scientific review highlights the potential benefits of intermittent and periodic fasting for promoting longer and healthier lives.

Research in zebrafish has shown that enhancing gut-specific telomerase expression can significantly delay aging throughout the body.

Research into heterochronic parabiosis (blood transfusion) has shown promising results in reversing some aspects of brain aging.

Research indicates that Unique Progerin C-terminal Peptide may treat Progeria. a rare genetic disorder characterized by accelerated aging.

The CALERIE phase 2 clinical trial indicates that long-term caloric restriction in healthy adults can slow the biological aging process.

Research shows that a natural extract from Salvia haenkei, known as Haenkenium improves longevity in mice by targeting cellular senescence

Research highlights that nucleophagy delays aging and preserves fertility through autophagic degradation and recycling of nuclear material.

Recent research has discovered that the inhibition of IL-11 can significantly extend both the healthspan and lifespan of mice.

A study published in Nature Aging has shown that the splicing fidelity modulates lifespan by interacting with the mTORC1 signaling...

Research highlights the anti-aging potential of rapamycin, which, when administered early in life, can extend lifespan and improve health.